The Lancet Doubles Down on anti-HCQ Fraud

The Lancet doubled down on its previous smear of Hydroxychloroquine (Mehra et al.), the main component of the effective COVID-19 treatments. On July 9, it published

Retraction and republication: cardiac toxicity of hydroxychloroquine in COVID-19
Christian Funck-Brentano, Lee S Nguyen, Joe-Elie Salem

Notice that  two of the three authors (Funck-Brentano and Salem) were also authors of the op-ed or comment to Mehra et al., published on the same day, which was also retracted.

This latest article re-uses the debunked Magagnoli et al., Rosenberg et al., and the tragicomic RECOVERY trial. In addition, it relies on an earlier fraudulent paper from the same authors Nguyen et al. (with additional co-authors).

Nguyen et al. , May 22

Cardiovascular Toxicities Associated with Hydroxychloroquine and Azithromycin: An Analysis of the World Health Organization Pharmacovigilance Database

Lee S. Nguyen, Charles Dolladille, Milou-Daniel Drici, Charlotte Fenioux, Joachim Alexandre, Jean-Paul Mira, Javid J. Moslehi, Dan M. Roden, Christian Funck-Brentano, and Joe-Elie Salem

It is another example of “database studies”. It uses fake methodology, described in gibberish. This is an excerpt (self-references are omitted):

 Association between hydroxychloroquine, azithromycin, and their combination with CV-ADR was assessed using reporting-odds-ratio (ROR) and information component (IC), an indicator value for disproportionate Bayesian reporting that compares observed and expected values to find associations between drugs and ADR. The lower end of the IC’s 95% credibility interval is IC025. It is considered significant when above 0.

ROR and IC are BS. The authors made up these quantities. The data is extracted from WHO’s VigiBase, using VigiAccess interface (its description can be found in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051262/). Similarly to FDA’s FAERS, WHO’s VigiBase (Vigi- comes from vigilance)contains mostly unverified reports of adverse effects, possibly linked to the drug. In addition, it contains complaints about drugs’ effectiveness and even administration procedures. The number of records has little relation to the drug safety. On July 13:

Paracetamol: 151, 575

Ibuprofen: 147,755

Azithromycin: 59,190

Hydroxychloroquine: 25,719

These are numbers of reports, not adjudicated cases. For HCQ, the largest group category is General disorders and administration site conditions (10422); the largest subcategory is Drug ineffective (6182).

The authors claim that they have found “76,822 ADR cases associated with hydroxychloroquine alone” – more cases than non-duplicate records. In less than 500 of these cases, HCQ was suspected in cardiovascular adverse reactions. Hydroxychloroquine with Azithromycin were suspected in 9 (nine) cases.

This paper contains no abstract and no subsection. Its only coherent conclusion “Hydroxychloroquine was also associated with potentially lethal HF [heart failure] when exposure was prolonged over several months” is neither relevant for a 5-day treatment for COVID-19 nor in agreement with other literature on the subject. Another oddity of this paper: it has only five references, three of which are self-references (i.e., references to papers including at least one of the authors).

As expected, the authors have hidden a conflict of interest. Christian Funck-Brentano is a Scientific Advisor to Banook Group (http://www.banookgroup.com/ap/webinar/). The Banook Group (formerly Cardiabase)  offers services in the field of cardiac safety (https://www.banookgroup.com/for-all/solutions/cardiac-safety/).

RECOVERY

A huge clinical trial RECOVERY, conducted in the Britain, would be comical if it were not tragic. The clinical researchers confused HCQ with another drug and gave their patients 6x higher dose than normal one (2,400 instead of 400 mg/day). It was tolerated well, but, on the balance, did not improve odds.

CQ/HCQ Cardiac Safety

In 2017, WHO investigated suspicions of cardiotoxicity of various anti-malarial drugs. It found CQ and HCQ to be exceptionally safe. In hundreds of millions of doses, only 11 deaths were reportedly associated with CQ or HCQ, four of which were clearly shown to be overdoses.

https://www.who.int/malaria/mpac/mpac-mar2017-erg-cardiotoxicity-report-session2.pdf

Exposure to chloroquine and hydroxychloroquine was reported in six and five cases of sudden death, respectively. In four of these cases, overdose was listed as the indication. Hydroxychloroquine was used to treat rheumatoid arthritis, systemic lupus erythematosus and small cell lung carcinoma in one case each.

Despite hundreds of millions of doses administered in the treatment of malaria, there have been no reports of sudden unexplained death associated with quinine, chloroquine or amodiaquine, although each drug causes QT/QTc interval prolongation.

via Science Defies Politics

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July 13, 2020 at 10:51PM

2 thoughts on “The Lancet Doubles Down on anti-HCQ Fraud”

  1. People should know that the proper use of vitamin C is a tested and verified safe, cheap and effective treatment, and prophylactic, against covid-19 — see orthomolecular d ot o r g (click on ‘Library’ and then ‘News Releases’ and read the editions from about February of 2020 on forward)

    A lot of this is based on Nobel laureate Linus Pauling’s pioneering work. HOWEVER….. everyone should keep the following in mind, especially now with the corona scamdemic going on: there are many bogus voices around who strive to distract the public from (1) the value of vitamin C therapy and (2) the fact that Pauling’s VALID work with vitamin C supplementation has been “falsified” by data distortions and lies, and he as a person (a double Nobel laureate) has been slandered as some deluded idiot by the criminal medical establishment and its countless quackwatch shills, lackeys, ignoramuses, and trolls for decades and it continues today — search for the scholarly report “2 Big Lies: No Vitamin Benefits & Supplements Are Very Dangerous” by Rolf Hefti (a published author of the Orthomolecular Medicine News organization). The same corrupt criminal people (and their uninformed followers) are behind the organized suppression, lies, and half-truths spread about the value of vitamin C therapy against covid-19 — see orthomolecular d ot o r g

    But you can’t discredit the facts with lies. That only exposes and discredits the liars (see citations above).

    The fact that we are dealing with a VERY CRIMINAL OFFICIAL POWER STRUCTURE (the Deep State, governments, WHO, official corporate medicine, CDC/Fauci, the mainstream media, paid off scientists, Bill Gates, etc) that constantly hoodwinks the unsuspecting public with MANY BIG LIES can easily be recognized by anyone with two working brain cells when reading this one sentence by a former US government official, Paul Craig Roberts, Ph.D., in his article ‘The Cost of Big Pharma’s Covid-19 Vaccine Will Be Paid in Lives and in Billions of Dollars’:

    “A corrupt establishment and media that can sell us 9/11, Saddam Hussein’s weapons of mass destruction, Iranian nukes, Assad’s use of chemical weapons, a Russian invasion of Ukraine, Russiagate and a large number of other lies can also sell us on locking up a successful treatment in the closet while we await a vaccine.”

    or from another article of his:

    “In “freedom and democracy” America there is only official truth, and it is a lie. […]. […] when I told the truth that Russiagate was a hoax, which it has proved to be, an anonymous website, possibly a CIA or NATO operation called “PropOrNot,” included this website among its fake list of 200 “Russian agents/dupes.” The Washington Post, a believed long-time CIA asset, hyped the PropOrNot revelation as if it were the truth. With “Russiagate” in full hype, the purpose was to scare readers away from those of us who were exposing the hoax. […]. The way those with agendas control the explanations is by shouting down those who provide objective accounts. Social media is part of the censorship. Explanations out of step with official ones are labeled “abusive,” and in “violation of community standards.” In other words, truth is unacceptble. […]. Everyone who uses social media is by their use supporting censorship. Facebook imposes fascist censorship in order to protect official explanations. The presstitutes and universities do the same. In America truth has lost its value. […]. Even a public health threat like coronavirus is politicized. […]. If you are Big Pharma, NIH, CDC, or the research professionals dependent on grants from these sources, you want a vaccine, not a cure. This means a long wait, assuming an effective and safe vaccine is possible. […]. The hydroxychloroquine (HCQ), zinc, and intravenous vitamin C treatments, which have proved to be effective, are badmouthed by Big Pharma and its minions. In other words, the profit agenda over-rides health care and the saving of lives. […]. It is all about money. There are no profits for Big Pharma or a chance for patents for Dr. Fauci unless inexpensive HCQ, zinc, and Vitamin C can be sidelined.”

    Also, if nothing else, watch this MUST-SEE documentary: is d o t gd/uQH5Lb

    And if you still do not think that covid-19 is a planned scamdemic ponder this statement by the American investigative reporter Jon Rappoport:

    “Since planes fly back and forth, and since all sorts of Westerners travel to the rainforests, why haven’t we seen whole native tribes wiped out by viruses from the deep dark streets of Brooklyn? It would even seem that viruses, common in, say, Norway, would cause trouble in Oregon. Why does it have to be “viruses from jungles?” Or other faraway places like China? […]. […] is it possible that jungles and Africa and China are typically chosen for virus fairy tales because, in the minds of many Westerners, they satisfy a requirement of “strange,” “different,” “primitive,” and so on? We’re talking theater here—and when you stage a propaganda play (fiction), you want to tap into the reflex instincts of the audience. The Hartford Virus, the Des Moines Virus, the Vancouver Virus just don’t fit the bill. Because they can’t drive up the fear that jungles or Africa or China can. […]. We NEVER hear killer virus stories about germs traveling from Europe and America to Asia and Africa. Why not? Because such a story won’t sell. It won’t bite. This is called a clue. It tells you that virus-stories are shaped and managed and written and managed and broadcast according to a plan that has nothing to do with actual disease.”

    But having true knowledge like that is not enough in itself, YOUR BEHAVIOR must reflect the implications of that knowledge…. ESPECIALLY NOW IN THE FACE OF THIS MASSIVE EVIL SCAM. As the American social critic Paul Rosenberg pointed out in his article ‘Nothing Changes As Long As You Obey’:

    “I hear the same complaints about politicians that you do. And while I understand them, the fact is that complaining accomplishes almost nothing. And there is a very simple reason why complaining has no real effect: BECAUSE THE COMPLAINERS KEEP RIGHT ON OBEYING. As long as you obey, the things you complain about will keep on happening.”

    And Edmund Burke said:

    “The only thing necessary for the triumph of evil is that good people do nothing.”

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