Best Covid Rx

Background from pioneering family Dr. Vladimir Zelenko:

Dr. Zelenko: You know, the Omicron variant or the Delta variant or any other of the variants – they’re all the same to me. The reason why I say that is: the difference in those variants is in the shape of the spike protein and its ability to get it into the cell. My focus has never been the virus getting into the cell — my focus has been to stop the virus from making copies of its genetic material — or viral replication. And that is the same pathway for all the variants.

By blocking the common pathway — the common denominator — called RNA-dependent RNA-polymerase — you actually inhibit all the variants simultaneously.

That’s why zinc, together with a zinc ionophore, is absolutely crucial. Because zinc blocks that enzyme. And the zinc ionophore allows for zinc to get into the cell. The most common zinc ionophores are hydroxychloroquine and ivermectin. But those are prescription. Due to governmental tyranny, they’re difficult to get.

And so there are over-the-counter options such as quercetin, which is a derivative of apple peels — it’s a bioflavonoid — together with Vitamin C that is an effective zinc ionophore or zinc delivery system or zinc “gun.” Proven by peer-reviewed papers on the NIH server. As well as EGCG, which is an extract from green tea, which does the same thing.

So my formulation of Z-Stack is based on quercetin, together with Vitamin C which delivers the zinc into the cell. And it also has Vitamin D. Vitamin D is important to upregulate your immune system so you’re healthy and robust and the virus won’t cause complications in most cases.

NIH (National Institutes of Health) Red wine: A drink to your heart

Red Wine: A Potent Antioxidant

For many years, the emphasis has been on the relationship between serum total cholesterol levels and the risk of CVD (Cardio-Vascular Disease). However, the focus has recently shifted to oxidative stress induced by reactive oxygen species (ROS) and nitrogen-reactive species as important key players in the etiology and pathogenesis of various chronic diseases, including CVD.[12] Antioxidant nutrients are believed to slow down the progression of atherosclerosis due to their ability to inhibit the damaging oxidative processes.[13,14] Epidemiological and prospective studies have shown that consumption of antioxidant vitamins such as vitamin E and ß-carotene could reduce the risk of CVD.[15] Clinical trials also suggest a reduced risk of CVD with vitamin E supplementation.[16] The protective effect of vitamin E can be ascribed to its antioxidant properties. Observations that men and women with CVD show lower levels of circulating antioxidants have led scientists to support the proposed protective role of antioxidants in the prevention and management of CVD.[13] Red wine-active principles like red wine polyphenols, resveratrol and quercetin have experimental cardioprotective properties[17] and may counter one of the mechanisms underlying its antioxidant potential. The cardioprotective properties of individual red wine components are discussed below.

Quercetin

Quercetin is one of the most important flavonoids present in red wine. The antioxidant and protective mechanisms in various ischemic conditions were proved by many researches. It has been reported that quercetin inhibited thrombocyte aggregation[53] and had an antihypertensive effect through vasodilator action on the vascular smooth muscles.[54] The studies that focused on the antioxidant efficiency of flavonoids against ischemia/reperfusion (I/R) injury have demonstrated that quercetin possesses robust protective effects in renal, cerebral and hepatic I/R models.[55–57] Quercetin was also demonstrated to improve the contractile function of the left ventricle in experimental myocardial infarction with subsequent 24-h reperfusion.[58] Ikizer et al. reported that quercetin has the capacity to protect the myocardial tissue against global ischemia and reperfusion injury. In instances where the molecule is administered for the purpose of acute therapy, this cardioprotective effect of a significant degree can be observed, and the protective action might be due to its antioxidant and cytoprotective actions.

Red wine alcohol promotes quercetin absorption and directs its metabolism

Tissue preparations were incubated in whole or dealcoholised red wine, diluted 1 : 1 with Krebs buffer for 20 min at 37°C, after which the mucosa was removed and processed for HPLC analysis. Tissues exposed to red wine had significantly higher amounts of both quercetin (× 3; P<0.001) and quercetin-3-O-glucoside (× 1.5; P<0.01) associated with them, compared with sacs incubated in the dealcoholised equivalent. In addition, both tamarixetin (T) and isorhamnetin (I), in the mucosal tissue from sacs exposed to the whole wine, were significantly elevated approximately two fold (P<0.05; P<0.01, respectively).

It is therefore plausible that the moderate alcohol content of red wine contributes to its beneficial health effects in humans by both increasing the absorption of quercetin and quercetin-3-O-glucoside and by channelling their metabolism towards O-methylation to yield compounds (T and I), which have potential protective effects against cancer and cardiovascular diseases.

My Comment

Even without this evidence I can attest to the benefits of daily red wine intake along with daily supplements of Zinc, Vitamins C and D. No viral symptoms yet, only occasional runny nose and sore throat easily resolved with saline sinus rinses, mouthwashes. lozenges and cough syrup.  And as I reported recently my serum test last month showed the highest rating for antibodies against the spike protein.  Anecdotal, but consistent with above scientific studies.

via Science Matters

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January 16, 2022 at 11:28AM

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